Gene: DCLRE1C

Alternate names for this Gene: A-SCID|DCLREC1C|RS-SCID|SCIDA|SNM1C

Gene Summary: This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 10

Location in Chromosome : 10p13

Description of this Gene: DNA cross-link repair 1C

Type of Gene: protein-coding

Gene: SUV39H2

Alternate names for this Gene: KMT1B

Gene Summary:

Gene is located in Chromosome: 10

Location in Chromosome : 10p13

Description of this Gene: suppressor of variegation 3-9 homolog 2

Type of Gene: protein-coding