Gene: DDX60L

Alternate names for this Gene: -

Gene Summary: This gene encodes a member of the DExD/H-box helicase family of proteins, a subset of the super family 2 helicases. Members of the DExD/H-box helicase family share a conserved functional core comprised of two RecA-like globular domains. These domains contain conserved motifs that mediate ATP binding, ATP hydrolysis, nucleic acid binding, and RNA unwinding. In addition to functions in RNA metabolism, members of this family are involved in anti-viral immunity and act as cytosolic sensors of viral nucleic acids. The protein encoded by this gene has been shown to inhibit hepatitis C virus replication in response to interferon stimulation in cell culture. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 4

Location in Chromosome : 4q32.3

Description of this Gene: DExD/H-box 60 like

Type of Gene: protein-coding

Gene: LOC107986198

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

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Description of this Gene:

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rs2710833 in DDX60L;LOC107986198 gene and Liver Cirrhosis PMID 20708005 2010 Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease.

rs2710833 in DDX60L;LOC107986198 gene and Non-alcoholic Fatty Liver Disease PMID 20708005 2010 Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease.