Gene: DEFB1

Alternate names for this Gene: BD1|DEFB-1|DEFB101|HBD1

Gene Summary: Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis.

Gene is located in Chromosome: 8

Location in Chromosome : 8p23.1

Description of this Gene: defensin beta 1

Type of Gene: protein-coding

rs2702945 in DEFB1 gene and Blood Protein Measurement PMID 29875488 2018 Genomic atlas of the human plasma proteome.

rs5743467 in DEFB1 gene and Kynurenine Measurement PMID 29317604 2018 Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics.

rs5743467 in DEFB1 gene and Major Depressive Disorder PMID 29317604 2018 Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics.

rs5743467 in DEFB1 gene and Unipolar Depression PMID 29317604 2018 Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics.