Gene: DEFB116

Alternate names for this Gene: DEFB-16

Gene Summary: Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions.

Gene is located in Chromosome: 20

Location in Chromosome : 20q11.21

Description of this Gene: defensin beta 116

Type of Gene: protein-coding

rs6061162 in DEFB116 gene and Smoking PMID 30643258 2019 Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.