Gene: DEFB127

Alternate names for this Gene: C20orf73|DEF-27|DEFB-27|DEFB27|bA530N10.2|hBD-27

Gene Summary: Defensins are cysteine-rich cationic polypeptides that are important in the immunologic response to invading microorganisms. The antimicrobial protein encoded by this gene is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20p13.

Gene is located in Chromosome: 20

Location in Chromosome : 20p13

Description of this Gene: defensin beta 127

Type of Gene: protein-coding

rs11087789 in DEFB127 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.