Gene: DEGS1

Alternate names for this Gene: DEGS|DEGS-1|DES1|Des-1|FADS7|HLD18|MIG15|MLD

Gene Summary: This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor.

Gene is located in Chromosome: 1

Location in Chromosome : 1q42.11

Description of this Gene: delta 4-desaturase, sphingolipid 1

Type of Gene: protein-coding