Gene: DEGS2

Alternate names for this Gene: C14orf66|DES2|FADS8

Gene Summary: This gene encodes a bifunctional enzyme that is involved in the biosynthesis of phytosphingolipids in human skin and in other phytosphingolipid-containing tissues. This enzyme can act as a sphingolipid delta(4)-desaturase, and also as a sphingolipid C4-hydroxylase.

Gene is located in Chromosome: 14

Location in Chromosome : 14q32.2

Description of this Gene: delta 4-desaturase, sphingolipid 2

Type of Gene: protein-coding

rs7157599 in DEGS2 gene and Mental deterioration PMID 23732972 2013 Genome-wide association study of cognitive decline in schizophrenia.

rs7157599 in DEGS2 gene and Sudden Cardiac Arrest PMID 21658281 2011 GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.

rs7157599 in DEGS2 gene and Sudden Cardiac Death PMID 21658281 2011 GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.