Gene: DGKG

Alternate names for this Gene: DAGK3|DGK-GAMMA

Gene Summary: This gene encodes an enzyme that is a member of the type I subfamily of diacylglycerol kinases, which are involved in lipid metabolism. These enzymes generate phosphatidic acid by catalyzing the phosphorylation of diacylglycerol, a fundamental lipid second messenger that activates numerous proteins, including protein kinase C isoforms, Ras guanyl nucleotide-releasing proteins and some transient receptor potential channels. Diacylglycerol kinase gamma has been implicated in cell cycle regulation and in the negative regulation of macrophage differentiation in leukemia cells. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 3

Location in Chromosome : 3q27.2-q27.3

Description of this Gene: diacylglycerol kinase gamma

Type of Gene: protein-coding

Gene: ETV5

Alternate names for this Gene: ERM

Gene Summary:

Gene is located in Chromosome: 3

Location in Chromosome : 3q27.2

Description of this Gene: ETS variant transcription factor 5

Type of Gene: protein-coding

rs73052033 in DGKG;ETV5 gene and Body mass index PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.