Gene: DGKZ
Alternate names for this Gene: DAGK5|DAGK6|DGK-ZETA|hDGKzeta
Gene Summary: The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and multiple transcript variants encoding distinct isoforms have been identified.
Gene is located in Chromosome: 11
Location in Chromosome : 11p11.2
Description of this Gene: diacylglycerol kinase zeta
Type of Gene: protein-coding
rs34406563 in
DGKZ gene and
Bone Density
PMID 29304378 2018 Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.
rs7951870 in
DGKZ gene and
Schizophrenia
PMID 31268507 2019 Association of Schizophrenia Risk With Disordered Niacin Metabolism in an Indian Genome-wide Association Study.
PMID 29483656 2018 Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.
PMID 26198764 2015 Genome-wide association study of schizophrenia in Ashkenazi Jews.