Gene: DLGAP2

Alternate names for this Gene: C8orf68|DAP2|ERICH1-AS1|SAPAP2

Gene Summary: The product of this gene is a membrane-associated protein that may play a role in synapse organization and signalling in neuronal cells. This gene is biallelically expressed in the brain, however, only the paternal allele is expressed in the testis (PMID:18055845). Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene is located in Chromosome: 8

Location in Chromosome : 8p23.3

Description of this Gene: DLG associated protein 2

Type of Gene: protein-coding

rs2404298 in DLGAP2 gene and Chronic Kidney Diseases PMID 29885931 2018 Genome-wide association studies suggest that APOL1-environment interactions more likely trigger kidney disease in African Americans with nondiabetic nephropathy than strong APOL1-second gene interactions.

rs17062789 in DLGAP2 gene and Creatinine clearance measurement PMID 26148204 2015 Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.

rs17062789 in DLGAP2 gene and HIV Infections PMID 26148204 2015 Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.

rs2404298 in DLGAP2 gene and Kidney Failure, Chronic PMID 29885931 2018 Genome-wide association studies suggest that APOL1-environment interactions more likely trigger kidney disease in African Americans with nondiabetic nephropathy than strong APOL1-second gene interactions.

rs10111688 in DLGAP2 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

rs1393703 in DLGAP2 gene and Narcolepsy PMID 19629137 2009 Genome-wide association database developed in the Japanese Integrated Database Project.

rs139288166 in DLGAP2 gene and Prostate carcinoma PMID 31095341 2020 Radiogenomics Consortium Genome-Wide Association Study Meta-Analysis of Late Toxicity After Prostate Cancer Radiotherapy.

rs28680850 in DLGAP2 gene and Triglycerides measurement PMID 24886709 2014 Amerindian-specific regions under positive selection harbour new lipid variants in Latinos.