Gene: DNAH8

Alternate names for this Gene: ATPase|SPGF46|hdhc9

Gene Summary: The protein encoded by this gene is a heavy chain of an axonemal dynein involved in sperm and respiratory cilia motility. Axonemal dyneins generate force through hydrolysis of ATP and binding to microtubules.

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.2

Description of this Gene: dynein axonemal heavy chain 8

Type of Gene: protein-coding

rs9380815 in DNAH8 gene and Adolescent idiopathic scoliosis PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

rs145974361 in DNAH8 gene and Ciliary Motility Disorders PMID 24307375 2014 Robust diagnostic genetic testing using solution capture enrichment and a novel variant-filtering interface.

rs9296260 in DNAH8 gene and Narcolepsy PMID 19629137 2009 Genome-wide association database developed in the Japanese Integrated Database Project.

rs9380815 in DNAH8 gene and SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3 PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.