Gene: DNLZ

Alternate names for this Gene: C9orf151|HEP|HEP1|TIMM15|ZIM17|bA413M3.2

Gene Summary:

Gene is located in Chromosome: 9

Location in Chromosome : 9q34.3

Description of this Gene: DNL-type zinc finger

Type of Gene: protein-coding

Gene: CARD9

Alternate names for this Gene: CANDF2|hCARD9

Gene Summary: The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined.

Gene is located in Chromosome: 9

Location in Chromosome : 9q34.3

Description of this Gene: caspase recruitment domain family member 9

Type of Gene: protein-coding

rs4073153 in DNLZ;CARD9 gene and Forced expiratory volume function PMID 30804560 2019 New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

rs4073153 in DNLZ;CARD9 gene and Vital capacity PMID 30804560 2019 New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.