Gene: DOK6

Alternate names for this Gene: DOK5L|HsT3226

Gene Summary: DOK6 is a member of the DOK (see DOK1; MIM 602919) family of intracellular adaptors that play a role in the RET (MIM 164761) signaling cascade (Crowder et al., 2004 [PubMed 15286081]).[supplied by OMIM, Mar 2008]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.154678.1, SRR1803612.137908.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000382713.10/ ENSP00000372160.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##

Gene is located in Chromosome: 18

Location in Chromosome : 18q22.2

Description of this Gene: docking protein 6

Type of Gene: protein-coding

rs4555246 in DOK6 gene and Chronic Kidney Diseases PMID 21931561 2011 Genetic association for renal traits among participants of African ancestry reveals new loci for renal function.

rs17184557 in DOK6 gene and Osteoporosis PMID 20548944 2010 An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits.