Gene: DPF3

Alternate names for this Gene: BAF45C|CERD4

Gene Summary: This gene encodes a member of the D4 protein family. The encoded protein is a transcription regulator that binds acetylated histones and is a component of the BAF chromatin remodeling complex. Alternate splicing results in multiple transcript variants encoding different isoforms.

Gene is located in Chromosome: 14

Location in Chromosome : 14q24.2

Description of this Gene: double PHD fingers 3

Type of Gene: protein-coding

rs7160830 in DPF3 gene and Adolescent idiopathic scoliosis PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

rs12887388 in DPF3 gene and Age related macular degeneration PMID 29346644 2018 Genome-wide analysis of disease progression in age-related macular degeneration.

rs74884082 in DPF3 gene and Atrial Fibrillation PMID 30061737 2018 Biobank-driven genomic discovery yields new insight into atrial fibrillation biology.

PMID 29892015 2018 Multi-ethnic genome-wide association study for atrial fibrillation.

rs61986330 in DPF3 gene and Body mass index PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

PMID 30239722 2019 Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.

rs202075571 in DPF3 gene and RDW - Red blood cell distribution width result PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs202075571 in DPF3 gene and Red cell distribution width determination PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs4903064 in DPF3 gene and Renal Cell Carcinoma PMID 31231134 2019 Sex specific associations in genome wide association analysis of renal cell carcinoma.

PMID 28598434 2017 We confirm the six known RCC risk loci and identify seven new loci at 1p32.3 (rs4381241, P=3.1 × 10<sup>-10</sup>), 3p22.1 (rs67311347, P=2.5 × 10<sup>-8</sup>), 3q26.2 (rs10936602, P=8.8 × 10<sup>-9</sup>), 8p21.3 (rs2241261, P=5.8 × 10<sup>-9</sup>), 10q24.33-q25.1 (rs11813268, P=3.9 × 10<sup>-8</sup>), 11q22.3 (rs74911261, P=2.1 × 10<sup>-10</sup>) and 14q24.2 (rs4903064, P=2.2 × 10<sup>-24</sup>).

rs7160830 in DPF3 gene and SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3 PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

rs10140566 in DPF3 gene and Tonometry PMID 29617998 2018 Genome-wide association analyses identify new loci influencing intraocular pressure.