Gene: DPP9

Alternate names for this Gene: DP9|DPLP9|DPP IX|DPRP-2|DPRP2

Gene Summary: This gene encodes a protein that is a member of the S9B family in clan SC of the serine proteases. The protein has been shown to have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Although the activity of this protein is similar to that of dipeptidyl peptidase 4 (DPP4), it does not appear to be membrane bound. In general, dipeptidyl peptidases appear to be involved in the regulation of the activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. Several transcript variants of this gene have been described but not fully characterized.

Gene is located in Chromosome: 19

Location in Chromosome : 19p13.3

Description of this Gene: dipeptidyl peptidase 9

Type of Gene: protein-coding

rs12610495 in DPP9 gene and Lung Diseases, Interstitial PMID 23583980 2013 Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.