Gene: DSN1

Alternate names for this Gene: C20orf172|KNL3|MIS13|dJ469A13.2|hKNL-3

Gene Summary: This gene encodes a kinetochore protein that functions as part of the minichromosome instability-12 centromere complex. The encoded protein is required for proper kinetochore assembly and progression through the cell cycle. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 20

Location in Chromosome : 20q11.23

Description of this Gene: DSN1 component of MIS12 kinetochore complex

Type of Gene: protein-coding

rs56317999 in DSN1 gene and Factor VII measurement PMID 30642921 2019 A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.