Gene: EDNRA
Alternate names for this Gene: ET-A|ETA|ETA-R|ETAR|ETRA|MFDA|hET-AR
Gene Summary: This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants.
Gene is located in Chromosome: 4
Location in Chromosome : 4q31.22-q31.23
Description of this Gene: endothelin receptor type A
Type of Gene: protein-coding