Gene: EEF1D

Alternate names for this Gene: EF-1D|EF1D|FP1047

Gene Summary: This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.

Gene is located in Chromosome: 8

Location in Chromosome : 8q24.3

Description of this Gene: eukaryotic translation elongation factor 1 delta

Type of Gene: protein-coding

Gene: TIGD5

Alternate names for this Gene: -

Gene Summary: The protein encoded by this gene belongs to the tigger subfamily of the pogo superfamily of DNA-mediated transposons in humans. These proteins are related to DNA transposons found in fungi and nematodes, and more distantly to the Tc1 and mariner transposases. They are also very similar to the major mammalian centromere protein B. The exact function of this gene is not known.

Gene is located in Chromosome: 8

Location in Chromosome : 8q24.3

Description of this Gene: tigger transposable element derived 5

Type of Gene: protein-coding

rs2242095 in EEF1D;TIGD5 gene and Acne Vulgaris PMID 29855537 2018 Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs.