Gene: ENTPD4

Alternate names for this Gene: LALP70|LAP70|LYSAL1|NTPDase-4|UDPase

Gene Summary: This gene encodes a member of the apyrase protein family. Apyrases are enzymes that catalyze the hydrolysis of nucleotide diphosphates and triphosphates in a calcium or magnesium-dependent manner. The encoded protein is an endo-apyrase and may play a role in salvaging nucleotides from lysosomes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and these isoforms may differ in divalent cation dependence and substrate specificity.

Gene is located in Chromosome: 8

Location in Chromosome : 8p21.3

Description of this Gene: ectonucleoside triphosphate diphosphohydrolase 4

Type of Gene: protein-coding

rs6557672 in ENTPD4 gene and Lymphocyte Count measurement PMID 22286170 2012 The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes.