Gene: ERLEC1
Alternate names for this Gene: C2orf30|CIM|CL24936|CL25084|HEL117|XTP3-B|XTP3TPB
Gene Summary: This gene encodes a resident endoplasmic reticulum (ER) protein that functions in N-glycan recognition. This protein is thought to be involved in ER-associated degradation via its interaction with the membrane-associated ubiquitin ligase complex. It also functions as a regulator of multiple cellular stress-response pathways in a manner that promotes metastatic cell survival. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 21.
Gene is located in Chromosome: 2
Location in Chromosome : 2p16.2
Description of this Gene: endoplasmic reticulum lectin 1
Type of Gene: protein-coding
Gene: GPR75-ASB3
Alternate names for this Gene: ASB-3|ASB3
Gene Summary: This locus represents naturally occurring read-through transcription between the neighboring GPR75 (G protein-coupled receptor 75) and ASB3 (ankyrin repeat and SOCS box containing 3) on chromosome 2. The transcript includes exons from both GPR75 and ASB3 and translation initiates in the 5' non-coding exon of GPR75. The resulting protein has a novel N-terminus but is otherwise identical to that encoded by ASB3.
Gene is located in Chromosome: 2
Location in Chromosome : 2p16.2
Description of this Gene: GPR75-ASB3 readthrough
Type of Gene: protein-coding
Gene: ASB3
Alternate names for this Gene: ASB-3
Gene Summary: The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants have been described for this gene.
Gene is located in Chromosome: 2
Location in Chromosome : 2p16.2
Description of this Gene: ankyrin repeat and SOCS box containing 3
Type of Gene: protein-coding