Gene: ETV6
Alternate names for this Gene: TEL|TEL/ABL|THC5
Gene Summary: This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.
Gene is located in Chromosome: 12
Location in Chromosome : 12p13.2
Description of this Gene: ETS variant transcription factor 6
Type of Gene: protein-coding