Gene: EZR

Alternate names for this Gene: CVIL|CVL|HEL-S-105|VIL2

Gene Summary: The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

Gene is located in Chromosome: 6

Location in Chromosome : 6q25.3

Description of this Gene: ezrin

Type of Gene: protein-coding

rs3212308 in EZR gene and Hair Color PMID 30531825 2018 Genome-wide study of hair colour in UK Biobank explains most of the SNP heritability.