Gene: F2RL2

Alternate names for this Gene: PAR-3|PAR3

Gene Summary: This gene encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple transcript variants that encode different isoforms.

Gene is located in Chromosome: 5

Location in Chromosome : 5q13.3

Description of this Gene: coagulation factor II thrombin receptor like 2

Type of Gene: protein-coding

Gene: IQGAP2

Alternate names for this Gene: -

Gene Summary: This gene encodes a member of the IQGAP family. The encoded protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. This protein interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. It also acts as a tumor suppressor and has been found to play a role in regulating innate antiviral responses. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 5

Location in Chromosome : 5q13.3

Description of this Gene: IQ motif containing GTPase activating protein 2

Type of Gene: protein-coding