Gene: FAM155A

Alternate names for this Gene: NLF-1

Gene Summary:

Gene is located in Chromosome: 13

Location in Chromosome : 13q33.3

Description of this Gene: family with sequence similarity 155 member A

Type of Gene: protein-coding

rs1018597 in FAM155A gene and Adolescent idiopathic scoliosis PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

rs61967180 in FAM155A gene and Body Height PMID 28552196 2017 Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits.

rs9888533 in FAM155A gene and Body mass index PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs11619840 in FAM155A gene and Diverticular Diseases PMID 30177863 2018 Genome-wide association analyses identify 39 new susceptibility loci for diverticular disease.

PMID 28585551 2017 In the combined Icelandic and Danish data sets we observe significant association of intronic variants in ARHGAP15 (Rho GTPase-activating protein 15; rs4662344-T: P=1.9 × 10<sup>-18</sup>, odds ratio (OR)=1.23) and COLQ (collagen-like tail subunit of asymmetric acetylcholinesterase; rs7609897-T: P=1.5 × 10<sup>-10</sup>, OR=0.87) with diverticular disease and in FAM155A (family with sequence similarity 155A; rs67153654-A: P=3.0 × 10<sup>-11</sup>, OR=0.82) with diverticulitis.

PMID 30661054 2019 Genome-wide association analysis of diverticular disease points towards neuromuscular, connective tissue and epithelial pathomechanisms.

rs67153654 in FAM155A gene and Diverticulitis PMID 28585551 2017 In the combined Icelandic and Danish data sets we observe significant association of intronic variants in ARHGAP15 (Rho GTPase-activating protein 15; rs4662344-T: P=1.9 × 10<sup>-18</sup>, odds ratio (OR)=1.23) and COLQ (collagen-like tail subunit of asymmetric acetylcholinesterase; rs7609897-T: P=1.5 × 10<sup>-10</sup>, OR=0.87) with diverticular disease and in FAM155A (family with sequence similarity 155A; rs67153654-A: P=3.0 × 10<sup>-11</sup>, OR=0.82) with diverticulitis.

PMID 28585551 2017 Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis.

rs144312179 in FAM155A gene and Malaria PMID 29381699 2018 Novel genetic polymorphisms associated with severe malaria and under selective pressure in North-eastern Tanzania.

rs7317862 in FAM155A gene and Non-obstructive azoospermia PMID 22197933 2011 A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia.

rs1018597 in FAM155A gene and SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3 PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

rs1539134 in FAM155A gene and Serum albumin measurement PMID 23281178 2013 A genome-wide assessment of variability in human serum metabolism.

rs140781040 in FAM155A gene and Squamous cell carcinoma of lung PMID 29924316 2018 Genome-wide association study of familial lung cancer.

rs2806519 in FAM155A gene and mathematical ability PMID 30038396 2018 Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.