Gene: FAM219A
Alternate names for this Gene: C9orf25
Gene Summary: The protein encoded by this gene has homologs that have been identified in mouse, macaque, etc organisms. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Gene is located in Chromosome: 9
Location in Chromosome : 9p13.3
Description of this Gene: family with sequence similarity 219 member A
Type of Gene: protein-coding
Gene: DNAI1
Alternate names for this Gene: CILD1|DIC1|ICS1|PCD
Gene Summary: This gene encodes a member of the dynein intermediate chain family. The encoded protein is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome. Alternative splicing results in multiple transcript variants.
Gene is located in Chromosome: 9
Location in Chromosome : 9p13.3
Description of this Gene: dynein axonemal intermediate chain 1
Type of Gene: protein-coding