Gene: FARS2

Alternate names for this Gene: COXPD14|FARS1|HSPC320|PheRS|SPG77|mtPheRS

Gene Summary: This gene encodes a protein that transfers phenylalanine to its cognate tRNA. This protein localizes to the mitochondrion and plays a role in mitochondrial protein translation. Mutations in this gene can cause combined oxidative phosphorylation deficiency 14 (Alpers encephalopathy). Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 6

Location in Chromosome : 6p25.1

Description of this Gene: phenylalanyl-tRNA synthetase 2, mitochondrial

Type of Gene: protein-coding

Gene: LYRM4

Alternate names for this Gene: C6orf149|CGI-203|COXPD19|ISD11

Gene Summary: The protein encoded by this gene is found in both mitochondria and the nucleus, where it binds cysteine desulfurase and helps free inorganic sulfur for Fe/S clusters. Disruption of this gene negatively impacts mitochondrial and cytosolic iron homeostasis.

Gene is located in Chromosome: 6

Location in Chromosome : 6p25.1

Description of this Gene: LYR motif containing 4

Type of Gene: protein-coding