Gene: FBXL13

Alternate names for this Gene: CFAP169|DRC6|Fbl13

Gene Summary: Members of the F-box protein family, such as FBXL13, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008].

Gene is located in Chromosome: 7

Location in Chromosome : 7q22.1

Description of this Gene: F-box and leucine rich repeat protein 13

Type of Gene: protein-coding

rs17135875 in FBXL13 gene and Diastolic blood pressure PMID 24165912 2013 Genome-wide association study identifies 8 novel loci associated with blood pressure responses to interventions in Han Chinese.

rs17135875 in FBXL13 gene and Diastolic blood pressure measurement PMID 24165912 2013 Genome-wide association study identifies 8 novel loci associated with blood pressure responses to interventions in Han Chinese.

rs17135875 in FBXL13 gene and Mean blood pressure PMID 24165912 2013 Genome-wide association study identifies 8 novel loci associated with blood pressure responses to interventions in Han Chinese.