Gene: FBXO34

Alternate names for this Gene: CGI-301|Fbx34

Gene Summary: Members of the F-box protein family, such as FBXO34, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008].

Gene is located in Chromosome: 14

Location in Chromosome : 14q22.3

Description of this Gene: F-box protein 34

Type of Gene: protein-coding

rs35070799 in FBXO34 gene and Galectin-3 measurement PMID 28240269 2017 Connecting genetic risk to disease end points through the human blood plasma proteome.

rs10129505 in FBXO34 gene and Protein measurement PMID 23056639 2012 A genome-wide association study of circulating galectin-3.

rs8022225 in FBXO34 gene and Uric acid measurement (procedure) PMID 31578528 2019 Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.

rs10146637 in FBXO34 gene and White Blood Cell Count procedure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.