Gene: FGA
Alternate names for this Gene: Fib2
Gene Summary: This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing.
Gene is located in Chromosome: 4
Location in Chromosome : 4q31.3
Description of this Gene: fibrinogen alpha chain
Type of Gene: protein-coding