Gene: FGF10

Alternate names for this Gene: -

Gene Summary: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing.

Gene is located in Chromosome: 5

Location in Chromosome : 5p12

Description of this Gene: fibroblast growth factor 10

Type of Gene: protein-coding

Gene: FGF10-AS1

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

rs104893885 in FGF10;FGF10-AS1 gene and Lacrimoauriculodentodigital syndrome PMID 16630169 2006 LADD syndrome is caused by FGF10 mutations.

PMID 16501574 2006 Mutations in different components of FGF signaling in LADD syndrome.