Gene: FGL1

Alternate names for this Gene: HFREP1|HP-041|HPS|LFIRE-1|LFIRE1

Gene Summary: Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene.

Gene is located in Chromosome: 8

Location in Chromosome : 8p22

Description of this Gene: fibrinogen like 1

Type of Gene: protein-coding