Gene: FHL2

Alternate names for this Gene: AAG11|DRAL|FHL-2|SLIM-3|SLIM3

Gene Summary: This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants encoding different isoforms have been identified.

Gene is located in Chromosome: 2

Location in Chromosome : 2q12.2

Description of this Gene: four and a half LIM domains 2

Type of Gene: protein-coding