Gene: FLI1

Alternate names for this Gene: BDPLT21|EWSR2|SIC-1

Gene Summary: This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 11

Location in Chromosome : 11q24.3

Description of this Gene: Fli-1 proto-oncogene, ETS transcription factor

Type of Gene: protein-coding

Gene: SENCR

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Gene Summary:

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