Gene: FLNC-AS1

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: FLNC

Alternate names for this Gene: ABP-280|ABP280A|ABPA|ABPL|CMH26|FLN2|MFM5|MPD4|RCM5

Gene Summary: This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 7

Location in Chromosome : 7q32.1

Description of this Gene: filamin C

Type of Gene: protein-coding

rs879255640 in FLNC-AS1;FLNC gene and CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 26 PMID 26666891 2016 Mutations in FLNC are Associated with Familial Restrictive Cardiomyopathy.