Gene: FMO4

Alternate names for this Gene: FMO2

Gene Summary: Metabolic N-oxidation of diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man. This results in a small subpopulation with reduced TMA N-oxidation capacity and causes fish odor syndrome (Trimethylaminuria). Three forms of the enzyme are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics.

Gene is located in Chromosome: 1

Location in Chromosome : 1q24.3

Description of this Gene: flavin containing dimethylaniline monoxygenase 4

Type of Gene: protein-coding