Gene: FN3K

Alternate names for this Gene: -

Gene Summary: A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way, fructosamines, are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of fructosamines which may result in deglycation.

Gene is located in Chromosome: 17

Location in Chromosome : 17q25.3

Description of this Gene: fructosamine 3 kinase

Type of Gene: protein-coding

Gene: TBCD

Alternate names for this Gene: PEBAT|SSD-1|tfcD

Gene Summary: Cofactor D is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.

Gene is located in Chromosome: 17

Location in Chromosome : 17q25.3

Description of this Gene: tubulin folding cofactor D

Type of Gene: protein-coding

rs2248894 in FN3K;TBCD gene and RDW - Red blood cell distribution width result PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs2248894 in FN3K;TBCD gene and Red cell distribution width determination PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.