Gene: FRS3

Alternate names for this Gene: FRS2-beta|FRS2B|FRS2beta|SNT-2|SNT2

Gene Summary: This gene encodes a substrate for the fibroblast growth factor receptor. The encoded protein is found in the peripheral plasma membrane and links fibroblast growth factor receptor stimulation to activators of Ras. The encoded protein down-regulates extracellular regulated kinase 2 through direct binding.

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.1

Description of this Gene: fibroblast growth factor receptor substrate 3

Type of Gene: protein-coding

rs3761781 in FRS3 gene and Corpuscular Hemoglobin Concentration Mean PMID 23222517 2012 Seventy-five genetic loci influencing the human red blood cell.

rs3761781 in FRS3 gene and Finding of Mean Corpuscular Hemoglobin PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs3761781 in FRS3 gene and Red Blood Cell Count measurement PMID 19862010 2009 Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.