Gene: FSTL4

Alternate names for this Gene: -

Gene Summary:

Gene is located in Chromosome: 5

Location in Chromosome : 5q31.1

Description of this Gene: follistatin like 4

Type of Gene: protein-coding

Gene: MIR1289-2

Alternate names for this Gene: MIRN1289-2|hsa-mir-1289-2

Gene Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Gene is located in Chromosome: 5

Location in Chromosome : 5q31.1

Description of this Gene: microRNA 1289-2

Type of Gene: ncRNA

rs73788091 in FSTL4;MIR1289-2 gene and Major Depressive Disorder PMID 27622933 2016 Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response.

rs73788091 in FSTL4;MIR1289-2 gene and Mood Disorders PMID 27622933 2016 Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response.

rs73788091 in FSTL4;MIR1289-2 gene and response to SSRI PMID 27622933 2016 Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response.