Gene: FUT6

Alternate names for this Gene: FCT3A|FT1A|Fuc-TVI|FucT-VI

Gene Summary: The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X, an E-selectin ligand. Mutations in this gene are a cause of fucosyltransferase-6 deficiency. Two transcript variants encoding the same protein have been found for this gene.

Gene is located in Chromosome: 19

Location in Chromosome : 19p13.3

Description of this Gene: fucosyltransferase 6

Type of Gene: protein-coding

rs12019136 in FUT6 gene and Age related macular degeneration PMID 26691988 2016 A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.

rs708686 in FUT6 gene and Biliary calculi PMID 30504769 2018 Genome-wide association meta-analysis yields 20 loci associated with gallstone disease.

rs10409772 in FUT6 gene and Blood Protein Measurement PMID 29875488 2018 Genomic atlas of the human plasma proteome.

PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.

rs778798 in FUT6 gene and Blood basophil count (lab test) PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs12019136 in FUT6 gene and Exudative age-related macular degeneration PMID 26691988 2016 A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.

rs12019136 in FUT6 gene and Geographic Atrophy PMID 26691988 2016 A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.

rs3760775 in FUT6 gene and VITAMIN B12 MEASUREMENT PMID 28334792 2017 GWAS identifies population-specific new regulatory variants in FUT6 associated with plasma B12 concentrations in Indians.

PMID 22367966 2012 Genome-wide association study identifies novel loci associated with serum level of vitamin B12 in Chinese men.

rs12019136 in FUT6 gene and exudative macular degeneration PMID 26691988 2016 A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.