Gene: FYN

Alternate names for this Gene: SLK|SYN|p59-FYN

Gene Summary: This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.

Gene is located in Chromosome: 6

Location in Chromosome : 6q21

Description of this Gene: FYN proto-oncogene, Src family tyrosine kinase

Type of Gene: protein-coding

rs2148710 in FYN gene and Aggressive behavior PMID 24489884 2014 Genome-wide association study of proneness to anger.

rs2148710 in FYN gene and Anger PMID 24489884 2014 Genome-wide association study of proneness to anger.

rs7758816 in FYN gene and Hypothyroidism PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs7757969 in FYN gene and Schizophrenia PMID 28991256 2017 Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia.

PMID 30285260 2019 Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.

rs2012071 in FYN gene and Systolic Pressure PMID 30578418 2019 Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.