Gene: G6PC2

Alternate names for this Gene: IGRP

Gene Summary: This gene encodes an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate, the terminal step in gluconeogenic and glycogenolytic pathways, allowing the release of glucose into the bloodstream. The family member encoded by this gene is found in pancreatic islets and does not exhibit phosphohydrolase activity, but it is a major target of cell-mediated autoimmunity in diabetes. Several alternatively spliced transcript variants of this gene have been described, but their biological validity has not been determined.

Gene is located in Chromosome: 2

Location in Chromosome : 2q31.1

Description of this Gene: glucose-6-phosphatase catalytic subunit 2

Type of Gene: protein-coding

Gene: SPC25

Alternate names for this Gene: AD024|SPBC25|hSpc25

Gene Summary: This gene encodes a protein that may be involved in kinetochore-microtubule interaction and spindle checkpoint activity.

Gene is located in Chromosome: 2

Location in Chromosome : 2q24.3

Description of this Gene: SPC25 component of NDC80 kinetochore complex

Type of Gene: protein-coding