Gene: GART

Alternate names for this Gene: AIRS|GARS|GARTF|PAIS|PGFT|PRGS

Gene Summary: The protein encoded by this gene is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Gene is located in Chromosome: 21

Location in Chromosome : 21q22.11

Description of this Gene: phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase

Type of Gene: protein-coding