Gene: GATAD2A

Alternate names for this Gene: p66alpha

Gene Summary:

Gene is located in Chromosome: 19

Location in Chromosome : 19p13.11

Description of this Gene: GATA zinc finger domain containing 2A

Type of Gene: protein-coding

Gene: MIR640

Alternate names for this Gene: MIRN640|hsa-mir-640

Gene Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Gene is located in Chromosome: 19

Location in Chromosome : 19p13.11

Description of this Gene: microRNA 640

Type of Gene: ncRNA

rs2965183 in GATAD2A;MIR640 gene and Breast Carcinoma PMID 29059683 2017 Association analysis identifies 65 new breast cancer risk loci.

rs4808199 in GATAD2A;MIR640 gene and Low density lipoprotein cholesterol measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

rs4808199 in GATAD2A;MIR640 gene and Non-alcoholic Fatty Liver Disease PMID 29385134 2018 Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers.

rs4808199 in GATAD2A;MIR640 gene and Serum LDL cholesterol measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

rs4808199 in GATAD2A;MIR640 gene and Serum total cholesterol measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

rs4808199 in GATAD2A;MIR640 gene and Triglycerides measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.