Gene: GATB

Alternate names for this Gene: COXPD41|HSPC199|PET112|PET112L

Gene Summary:

Gene is located in Chromosome: 4

Location in Chromosome : 4q31.3

Description of this Gene: glutamyl-tRNA amidotransferase subunit B

Type of Gene: protein-coding

rs12647420 in GATB gene and Intelligence PMID 29844566 2018 Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

PMID 29942086 2018 Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.

PMID 29326435 2019 A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.

rs376766195 in GATB gene and Mitochondrial cardiomyopathy PMID 30283131 2018 Pathogenic variants in glutamyl-tRNAGln amidotransferase subunits cause a lethal mitochondrial cardiomyopathy disorder.