Gene: GCKR

Alternate names for this Gene: FGQTL5|GKRP

Gene Summary: This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).

Gene is located in Chromosome: 2

Location in Chromosome : 2p23.3

Description of this Gene: glucokinase regulator

Type of Gene: protein-coding

Gene: FNDC4

Alternate names for this Gene: FRCP1

Gene Summary:

Gene is located in Chromosome: 2

Location in Chromosome : 2p23.3

Description of this Gene: fibronectin type III domain containing 4

Type of Gene: protein-coding

rs780090 in GCKR;FNDC4 gene and Arthritis, Gouty PMID 23263486 2013 Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.

rs780090 in GCKR;FNDC4 gene and Gout PMID 23263486 2013 Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.

rs780090 in GCKR;FNDC4 gene and Serum total cholesterol measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

rs780090 in GCKR;FNDC4 gene and Triglycerides measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.