Gene: GCOM1

Alternate names for this Gene: GRINL1A|Gcom2|MYZAP|MYZAP-POLR2M|gcom

Gene Summary: This locus represents naturally occurring readthrough transcription between the neighboring MYZAP (myocardial zonula adherens protein) and POLR2M (polymerase (RNA) II (DNA directed) polypeptide M) genes on chromosome 15. Alternative splicing results in multiple readthrough transcript variants. Readthrough variants may encode proteins that share sequence identity with the upstream gene product or with both the upstream and downstream gene products. Some readthrough transcript variants are also expected to be candidates for nonsense-mediated decay (NMD).

Gene is located in Chromosome: 15

Location in Chromosome : 15q21.3

Description of this Gene: GRINL1A complex locus 1

Type of Gene: protein-coding

Gene: MYZAP

Alternate names for this Gene: GCOM1|Gup|MYOZAP

Gene Summary: This gene encodes a protein that is abundantly expressed in cardiac tissue. The encoded protein localizes to intercalated discs in cardiomyocytes and functions as an activator of Rho-dependent serum-response factor signaling. Alternative splicing results in multiple transcript variants. Readthrough transcription also exists between this gene and the neighboring downstream gene POLR2M (polymerase (RNA) II (DNA directed) polypeptide M) and is represented with GeneID: 145781.

Gene is located in Chromosome: 15

Location in Chromosome : 15q21.3

Description of this Gene: myocardial zonula adherens protein

Type of Gene: protein-coding