Gene: GGPS1

Alternate names for this Gene: GGPPS|GGPPS1

Gene Summary: This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found for this gene.

Gene is located in Chromosome: 1

Location in Chromosome : 1q42.3

Description of this Gene: geranylgeranyl diphosphate synthase 1

Type of Gene: protein-coding

Gene: TBCE

Alternate names for this Gene: HRD|KCS|KCS1|PEAMO|pac2

Gene Summary: Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene.

Gene is located in Chromosome: 1

Location in Chromosome : 1q42.3

Description of this Gene: tubulin folding cofactor E

Type of Gene: protein-coding