Gene: GLIS1

Alternate names for this Gene: -

Gene Summary: GLIS1 is a GLI (MIM 165220)-related Kruppel-like zinc finger protein that functions as an activator and repressor of transcription (Kim et al., 2002 [PubMed 12042312]).[supplied by OMIM, Mar 2008]. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK090634.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968968, SAMEA1970526 [ECO:0000350] ##Evidence-Data-END##

Gene is located in Chromosome: 1

Location in Chromosome : 1p32.3

Description of this Gene: GLIS family zinc finger 1

Type of Gene: protein-coding

rs17387330 in GLIS1 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs1111658 in GLIS1 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

rs1879734 in GLIS1 gene and Mitral Valve Prolapse Syndrome PMID 26301497 2015 Genetic association analyses highlight biological pathways underlying mitral valve prolapse.