Gene: GLS2

Alternate names for this Gene: GA|GLS|LGA|hLGA

Gene Summary: The protein encoded by this gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. Originally thought to be liver-specific, this protein has been found in other tissues as well. Alternative splicing results in multiple transcript variants that encode different isoforms.

Gene is located in Chromosome: 12

Location in Chromosome : 12q13.3

Description of this Gene: glutaminase 2

Type of Gene: protein-coding

Gene: SPRYD4

Alternate names for this Gene: -

Gene Summary:

Gene is located in Chromosome: 12

Location in Chromosome : 12q13.3

Description of this Gene: SPRY domain containing 4

Type of Gene: protein-coding

rs2657879 in GLS2;SPRYD4 gene and Amino acids measurement PMID 26068415 2015 Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.

PMID 27005778 2016 Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.

PMID 30659259 2019 Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population.

rs2657879 in GLS2;SPRYD4 gene and Fasting blood glucose measurement PMID 22885924 2012 Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.

rs2657879 in GLS2;SPRYD4 gene and Fasting blood sugar result PMID 22885924 2012 Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.

rs2657879 in GLS2;SPRYD4 gene and Glucose measurement PMID 21886157 2011 Human metabolic individuality in biomedical and pharmaceutical research.

rs2657879 in GLS2;SPRYD4 gene and Glutamine measurement PMID 30659259 2019 Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population.

rs2657879 in GLS2;SPRYD4 gene and Protein measurement PMID 27005778 2016 Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.

rs1043011 in GLS2;SPRYD4 gene and Serum albumin measurement PMID 22286219 2012 Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

rs2657879 in GLS2;SPRYD4 gene and elevated blood glucose level PMID 21886157 2011 Human metabolic individuality in biomedical and pharmaceutical research.