Gene: GLT6D1

Alternate names for this Gene: GLTDC1|GT6M7

Gene Summary: The GT6 glycosyltransferases gene family, which includes the ABO blood group (ABO; MIM 110300) and GLT6D1, shows a complex evolution pattern, with multiple events of gain and loss in different mammal species. In humans, the ABO gene is considered the sole functional member, although the O allele is null and is fixed in certain populations (summary by Casals et al. (2009) [PubMed 19218399]).[supplied by OMIM, Jan 2011]. ##Evidence-Data-START## Transcript exon combination :: AY336054.1, SRR5189667.186835.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874, SAMEA2158188 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000371763.6/ ENSP00000360829.1 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END##

Gene is located in Chromosome: 9

Location in Chromosome : 9q34.3

Description of this Gene: glycosyltransferase 6 domain containing 1

Type of Gene: protein-coding

rs1537415 in GLT6D1 gene and Periodontitis PMID 19897590 2010 The associated rare G allele of rs1537415 showed an enrichment of 10% in periodontitis cases (48.4% in comparison with 38.8% in controls).

rs1537415 in GLT6D1 gene and Periodontosis PMID 19897590 2010 A genome-wide association study identifies GLT6D1 as a susceptibility locus for periodontitis.